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Health-related quality of life in preschool children with Type 1 diabetes

F Sundberg1, P Sand, G Forsander

  • 1Diabetes Unit, The Queen Silvia Children's Hospital/Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Paediatrics, Institution of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Diabetic Medicine : a Journal of the British Diabetic Association
|August 2, 2014
PubMed

Insights

Very young children with Type 1 diabetes mellitus experience lower health-related quality of life compared to healthy peers. This highlights the need for quality of life screening in all children with diabetes.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Quality of Life Research

Background:

  • Type 1 diabetes mellitus (T1DM) is a chronic condition affecting children.
  • Assessing health-related quality of life (HRQoL) is crucial for understanding the holistic impact of T1DM in pediatric populations.
  • Limited data exists on HRQoL in very young children (<7 years) with T1DM.

Purpose of the Study:

  • To compare HRQoL in children under 7 years with T1DM versus healthy controls.
  • To examine correlations between HRQoL and insulin treatment/glycemic control in children with T1DM.

Main Methods:

  • A cohort of 24 children with T1DM (mean age 4.5) and 27 healthy children (mean age 4.6) participated.
  • Participants completed the Pediatric Quality of Life Inventory 4.0 Generic Core Scales.
  • Children with T1DM also completed the Pediatric Quality of Life Inventory 3.0 Type 1 Diabetes Module, with HbA1c and glucose meter data collected.

Main Results:

  • Children with T1DM had significantly lower parent-rated generic HRQoL scores (80 vs 91, P=0.003) compared to healthy children.
  • The disparity was more pronounced in children under 5 years (79 vs 93, P=0.004).
  • 22% of parents of children with T1DM rated their child's HRQoL as a concern; 40% of children aged 5-7 with T1DM rated their own HRQoL similarly.

Conclusions:

  • Very young children with T1DM exhibit a significantly reduced generic HRQoL compared to healthy peers.
  • The findings support the recommendation for routine HRQoL screening in all children diagnosed with T1DM, irrespective of age.
Abstract

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