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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

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Impact of echocardiographic left ventricular geometry on clinical prognosis

Carl J Lavie1, Dharmendrakumar A Patel2, Richard V Milani3

  • 1Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-University of Queensland School of Medicine, New Orleans, LA, USA; Department of Preventive Medicine, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.

Progress in Cardiovascular Diseases
|August 2, 2014
PubMed

Insights

Abnormal left ventricular geometry, including left ventricular hypertrophy (LVH), elevates cardiovascular risk. Regression of LVH is beneficial, while concentric remodeling (CR) may progress to LVH or normalize.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Clinical Cardiology

Background:

  • Abnormal left ventricular (LV) geometry, particularly LV hypertrophy (LVH), is linked to heightened risks of major cardiovascular (CV) events and mortality.
  • LVH is an independent predictor of adverse CV outcomes, including heart failure, coronary heart disease, stroke, and sudden cardiac death.

Purpose of the Study:

  • To review risk factors and consequences of LVH.
  • To examine the risks associated with concentric remodeling (CR).
  • To evaluate evidence on LVH regression and CR progression versus normalization.

Main Methods:

  • Literature review of studies on LV geometry, LVH, and CR.
  • Analysis of risk factors, clinical outcomes, and therapeutic implications.
  • Examination of the association between LV geometry and left atrial enlargement.

Main Results:

  • LVH significantly increases the risk of CV morbidity and mortality.
  • Concentric remodeling (CR) carries its own risks and may progress to LVH.
  • Regression of LVH is associated with improved CV outcomes.

Conclusions:

  • Abnormal LV geometry, including LVH and CR, represents a significant CV risk.
  • Understanding the progression and regression of these structural changes is crucial for patient management.
  • Combined structural cardiac abnormalities, like LVH and left atrial enlargement, may have synergistic adverse effects.

Keywords:
Cardiovascular EventsEchocardiographyLeft Ventricular Hypertrophy

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