Related Experiment Video

Updated: Apr 26, 2026

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection
07:24

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection

Published on: January 16, 2026

319

Metastatic meningiomas: an unusual clinical and pathological diagnosis with highly variable outcome

Fabien Forest1, Sid-Ali Berremila, Cezar Gyenes

  • 1Service d'anatomie et cytologie pathologiques, Centre Hospitalier Universitaire de Saint-Etienne, Hôpital Nord., 42055, Saint Etienne Cedex2, France, fabienforest@gmail.com.

Journal of Neuro-Oncology
|August 2, 2014
PubMed

Insights

Metastatic meningioma, though rare, presents diagnostic challenges. This study highlights aggressive meningiomas that metastasize, emphasizing the need for updated classifications beyond benign histology.

Area of Science:

  • Neuro-oncology
  • Pathology
  • Oncology

Background:

  • Metastatic meningioma is an uncommon event, often posing diagnostic difficulties.
  • The current WHO 2007 classification may not fully capture the metastatic potential of certain meningiomas.

Observation:

  • This retrospective study identified cases of metastatic meningioma.
  • Three patients with a history of meningioma surgery developed liver tumors with bone metastasis or lung metastases years later.

Findings:

  • Clinical and pathological diagnosis of metastatic meningioma can be challenging.
  • Histologically benign meningiomas can exhibit aggressive behavior and metastasize.
  • Metastatic meningiomas are distinct from haemangiopericytomas.

Implications:

  • The findings suggest a need to reconsider the classification of meningiomas, particularly those with aggressive clinical behavior.
  • Awareness of metastatic potential is crucial for accurate diagnosis and patient management.
  • Further research is warranted to identify predictive markers for meningioma metastasis.

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.3K
Translational Orthotopic Models of Glioblastoma Multiforme07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

3.7K

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
189
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
9
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
10