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Usefulness of the apparent diffusion coefficient (ADC) for predicting the consistency of intracranial meningiomas
Akira Yogi1, Tomomi Koga1, Kimei Azama1
1Department of Radiology, Graduated School of Medical Science, University of the Ryukyus, Okinawa, Japan.
Abstract:
Meningioma consistency is an important factor for surgical treatment. Tumor cellularity and fibrous tissue contribute to the consistency of tumors, and it is proposed that the minimum apparent diffusion coefficient (ADC) value is significantly correlated with meningioma consistency. Twenty-seven consecutive patients with 28 meningiomas were retrospectively enrolled. Minimum ADC values in meningiomas with a hard consistency were significantly lower than those with a soft consistency. The minimum ADC value might have clinical use as a predictor of meningioma consistency.
Insights
Minimum apparent diffusion coefficient (ADC) values can predict meningioma consistency. Lower ADC values indicate harder tumors, aiding surgical planning for meningiomas.
Area of Science:
- Neurosurgery
- Radiology
- Oncology
Background:
- Meningioma consistency is crucial for surgical intervention.
- Tumor cellularity and fibrous tissue influence meningioma consistency.
- Apparent diffusion coefficient (ADC) is a quantitative MRI metric.
Purpose of the Study:
- To investigate the correlation between minimum ADC values and meningioma consistency.
- To assess the potential of ADC values as a predictor of tumor consistency.
Main Methods:
- Retrospective analysis of 28 meningiomas from 27 patients.
- Measurement of minimum ADC values in all enrolled meningiomas.
- Correlation analysis between minimum ADC values and surgically determined tumor consistency (hard vs. soft).
Main Results:
- A significant inverse correlation was found between minimum ADC values and meningioma consistency.
- Meningiomas with hard consistency exhibited significantly lower minimum ADC values compared to soft meningiomas.
Conclusions:
- Minimum ADC values show potential as a non-invasive predictor of meningioma consistency.
- This finding may assist in preoperative surgical planning for meningioma patients.
