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Intra-aneurysmal flow patterns: illustrative comparison among digital subtraction angiography, optical flow, and
O Brina1, R Ouared1, O Bonnefous2
1From the Interventional Neuroradiology Unit (O. Brina, R.O., P. Bouillot, K.-O.L., V.M.P.), Service of Neuroradiology.
AJNR. American Journal of Neuroradiology
|August 2, 2014
Summary
Optical flow imaging, a novel technique, shows consistent results with computational fluid dynamics for evaluating intracranial aneurysm hemodynamics. This method enhances visualization of blood flow patterns in digital subtraction angiography, aiding in patient evaluation.
Area of Science:
- Medical Imaging
- Biomedical Engineering
- Cerebrovascular Research
Background:
- Digital subtraction angiography (DSA) is the standard for vascular imaging in endovascular treatments.
- Optical flow imaging offers a potential method for assessing cerebral hemodynamics via DSA.
- Intracranial aneurysms require precise hemodynamic evaluation for effective treatment.
Purpose of the Study:
- To compare flow patterns derived from optical flow imaging during angiography with computational fluid dynamics (CFD) in intracranial aneurysms.
- To assess the diagnostic consistency of optical flow imaging against established methods.
Main Methods:
- Analyzed 21 patients with unruptured saccular intracranial aneurysms undergoing diagnostic angiography.
- Utilized high-frame-rate DSA to derive intra-aneurysmal velocity fields using optical flow principles.
- Performed CFD modeling with patient-specific boundary conditions derived from optical flow data from DSA and 3D rotational angiography.
Main Results:
- Optical flow imaging and CFD showed matching flow patterns in 14 out of 21 patients (κ = .91).
- Optical flow images matched regular DSA in 8 out of 14 patients (observer κ = 0.87).
- Inconclusive flow patterns were observed in 7 patients, potentially due to suboptimal projection angles.
Conclusions:
- DSA-based optical flow imaging is qualitatively consistent with CFD for evaluating intra-aneurysmal flow dynamics.
- This technique may improve visualization of flow patterns, especially when contrast motion is subtle.
- Optical flow imaging presents a promising diagnostic tool for evaluating intra-aneurysmal flow and future patient management.
