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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
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Neurological disorders and inflammatory bowel diseases
Giovanni Casella1, Gian Eugenio Tontini1, Gabrio Bassotti1
1Giovanni Casella, Vittorio Baldini, Medical Department, Desio Hospital, 20033 Desio, Italy.
World Journal of Gastroenterology
|August 2, 2014
Summary
Neurologic disorders affect 3% of inflammatory bowel disease (IBD) patients, often preceding GI symptoms. This review details IBD-related neurological complications, including drug-induced conditions, their presentation, and causes.
Area of Science:
- Gastroenterology
- Neurology
- Pharmacology
Background:
- Extraintestinal manifestations affect one-third of inflammatory bowel disease (IBD) patients.
- Neurologic disorders are infrequent (3%) but significant causes of morbidity in IBD.
- Immunosuppressant and biologic therapies may contribute to neurological complications.
Purpose of the Study:
- To review the main features of neurological complications associated with IBD.
- To focus on drug-related neurological disorders in IBD patients.
- To examine clinical presentation and pathophysiological mechanisms.
Main Methods:
- Comprehensive literature review.
- Analysis of clinical presentations.
- Exploration of pathophysiological mechanisms.
Main Results:
- Neurological disorders are a recognized, though uncommon, complication of IBD.
- Drug therapies used for IBD can precipitate various neurological conditions.
- Understanding these complications is crucial for diagnosis and management.
Conclusions:
- Neurological manifestations in IBD require careful consideration.
- Drug-induced neurological disorders are an important aspect of IBD management.
- Further research into pathogenesis and treatment is warranted.
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