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Updated: Apr 26, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
Published on: March 17, 2016
Metabolic syndrome in breast cancer
Víctor Manuel Vargas-Hernández1, Vm Vargas-Aguilar1, Mario Adanm Moreno-Eutimio1
1Investigations Division, Hospital Juárez de México, México city, México.
Abstract:
Breast Cancer is a heterogeneous disease, progressive, currently, are classified according to in pattern of gene expression luminal A, luminal B, basal and HER-2neu + and Triple-negative, 75% to 80% have receptors positive hormonal and 15% to 20% are positive for hER-2neu and 10% to 20% are triple negative, with hormone receptor negative and HER2-neu and their diagnostic is made by exclusion, the Metabolic Syndrome is related to a higher incidence of these cancers where the insulin-leptin axis-adiponectin are implicated in carcinogenesis.
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