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Updated: Apr 26, 2026

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
Published on: January 16, 2026
Minimal-access left ventricular assist device implantation.
Anson Cheung1, Jia-Lin Soon, Jamil Bashir
1From the Division of *Cardiovascular Surgery, and †Department of Cardiology, St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
Minimally invasive surgery for left ventricular assist device (LVAD) implantation is feasible, offering shorter cardiopulmonary bypass (CPB) times. This approach may reduce complications during future cardiac transplantation.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Procedures
- Mechanical Circulatory Support
Background:
- Left ventricular assist device (LVAD) implantation traditionally involves a full sternotomy and cardiopulmonary bypass (CPB).
- Minimally invasive surgery (MIS) aims to reduce surgical trauma through smaller incisions and potentially shorter CPB times.
Purpose of the Study:
- To evaluate the feasibility and outcomes of minimally invasive surgery (MIS) for left ventricular assist device (LVAD) implantation.
- To compare MIS LVAD implantation with the traditional sternotomy approach.
Main Methods:
- Retrospective review of 42 LVAD implantations, comparing 25 MIS procedures with 17 sternotomy procedures.
- MIS approach varied by device: three incisions for HeartMate II, two for HeartWare.
- Four HeartWare devices were implanted off-pump, three via MIS.
Main Results:
- Minimally invasive surgery (MIS) LVAD patients experienced significantly shorter cardiopulmonary bypass (CPB) times (51.4 vs. 83.6 minutes, P=0.014).
- A trend towards lower red blood cell and platelet transfusion requirements was observed in the MIS group.
- Overall survival was 81% at mean follow-up of 495 days; 30-day mortality was 9.5%.
Conclusions:
- Minimally invasive surgery (MIS) is a feasible approach for left ventricular assist device (LVAD) implantation.
- Shorter CPB duration and potential off-pump implantation in MIS may offer advantages.
- Avoiding sternotomy in LVAD procedures may reduce adhesions for subsequent cardiac transplantation.
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