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Assessing the ability of an immunization information system to prevent overimmunization of pediatric influenza
Cristi A Carlton1, Rachel C Potter, Patricia A Vranesich
1Michigan Department of Community Health, Lansing.
Insights
Using immunization information systems (IIS) like MCIR can prevent overvaccination in children. This study shows MCIR
Area of Science:
- Public Health
- Immunization Practices
- Health Informatics
Background:
- The Advisory Committee on Immunization Practices (ACIP) provides annual influenza vaccine recommendations.
- ACIP offered two distinct approaches for determining 2-dose influenza vaccination for children aged 6 months to 8 years between 2011 and 2013.
- One approach disregarded prior vaccination history, while the other utilized complete immunization records, often found in immunization information systems (IIS).
Purpose of the Study:
- To compare the number of children recommended for two influenza vaccine doses under each ACIP approach.
- To assess the potential for influenza vaccine over-immunization in Michigan children.
- To evaluate the impact of using the Michigan Care Improvement Registry (MCIR) in preventing over-immunization.
Main Methods:
- Cross-sectional analysis of influenza seasons from 2011-2012 to 2013-2014.
- Utilized MCIR data, including seasonal influenza and 2009 H1N1 monovalent vaccine doses.
- Analyzed data for over 900,000 children aged 6 months to 8 years per season.
Main Results:
- The study identified significant numbers of children potentially receiving unnecessary second influenza vaccine doses.
- MCIR usage could have prevented over-immunization for 70,323 children in 2011-2012, 126,076 in 2012-2013, and 81,635 in 2013-2014.
- Quantified the difference in 2-dose recommendations between the two ACIP approaches.
Conclusions:
- This is the first study to use an IIS to quantify differences in ACIP's 2-dose influenza vaccine recommendations.
- MCIR's comprehensive immunization history and forecasting minimize over-immunization and offer cost-saving potential.
- Highlights the value of centralized IIS data for providers, public health, and caregivers.
Context:
The Advisory Committee on Immunization Practices (ACIP) publishes annual recommendations for the prevention and control of seasonal influenza. Between 2011 and 2013, the ACIP recommended 2 approaches that providers could use to determine how many influenza vaccine doses children aged 6 months through 8 years should receive. One did not consider doses received prior to the 2010-2011 season; the other considered complete influenza immunization history, such as that available in immunization information system (IIS).
Objectives:
To use Michigan's IIS, the Michigan Care Improvement Registry (MCIR), to compare the number of children recommended to receive 2 doses of influenza vaccine under each ACIP approach, and to determine the potential for overimmunization of Michigan children with influenza vaccine if providers do not use the data in MCIR.
Design:
Cross-sectional analysis in the 2011-2012 to 2013-2014 influenza seasons.
Setting:
We used the seasonal influenza and 2009 H1N1 monovalent vaccine doses in MCIR to determine the number of influenza vaccine doses children should receive using both ACIP approaches each season.
Participants:
We analyzed data for more than 900 000 children aged 6 months through 8 years in each influenza season.
Main Outcome Measure:
Number of children recommended 2 doses of influenza vaccine using each ACIP approach in each influenza season.
Results:
Our evaluation showed that using MCIR could prevent the overimmunization with a second influenza vaccine dose for 70 323 children during the 2011-2012 influenza season, 126 076 children during the 2012-2013 season, and 81 635 children during the 2013-2014 season.
Conclusions:
This is the first study to use an IIS to quantify the difference between ACIP's approaches for 2-dose influenza vaccine recommendations. The immunization history and 2-dose forecasting algorithm available through MCIR minimizes overimmunization and has potential cost-saving implications. Our study illustrates the value of a centralized repository provided by IISs to immunization providers, public health, and caregivers.
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