Optogenetics: opsins and optical interfaces in neuroscience
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Updated: Apr 26, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
Published on: January 15, 2015
Abstract:
Optogenetics is defined as the integration of optics and genetics to control well-defined events within specified cells of living tissue. In this introduction, we focus on the basic techniques necessary for employing microbial opsins as optogenetic tools in mammalian brains. We provide a guide for the fundamentals of optogenetic application-selecting an opsin, implementing expression of opsins based on the neuroscientific experimental requirements, and adapting the corresponding optical hardware for delivery of light into mammalian brains.
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