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Related Experiment Video

Updated: Apr 26, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
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Developing a core outcome set for hip fracture trials.

K L Haywood1, X L Griffin2, J Achten3

  • 1Warwick Medical School, Royal College of Nursing Research Institute (RCNRI), University of Warwick, Gibbet Hill Road, CV4 7AL, UK.

The Bone & Joint Journal
|August 3, 2014
PubMed
Summary

A UK consensus established a core outcome set (COS) for hip fracture trials, standardizing key health outcomes. This aims to improve clinical research design and evidence synthesis for better patient care.

Keywords:
Fragility hip fracture; Core outcome sets; Clinical trials

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Area of Science:

  • Orthopedics
  • Clinical Trials
  • Health Outcomes Research

Background:

  • Lack of consensus on core health outcomes hinders clinical research and evidence synthesis.
  • Hip fracture trials require standardized outcome reporting for improved study design.

Framework:

  • Modified nominal group technique used to achieve consensus.
  • Consensus required a 70% agreement threshold for outcome domains and assessment methods.

Implementation:

  • Participants reviewed evidence synthesis and questionnaires prior to a consensus meeting.
  • Facilitated discussion and closed voting determined the final core outcome set.

Implications:

  • A five-domain core outcome set (COS) for hip fracture trials was established: mortality, pain, activities of daily living, mobility, and health-related quality of life (HRQL).
  • Recommended minimum measures include single-item mortality and mobility assessments, and the EuroQoL EQ-5D for HRQL.
  • This standardized COS will enhance hip fracture clinical trial comparability and evidence synthesis.