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Updated: Apr 26, 2026

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
MR imaging in cirrhosis and hepatocellular carcinoma
Daniel C Barr1, Hero K Hussain1
1Department of Radiology/MRI, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Abstract:
Hepatocellular carcinoma (HCC) is the fastest growing cause of cancer-related death in the United States. Cirrhosis is the most important risk factor for HCC. Dynamic contrast-enhanced magnetic resonance (MR) imaging is the modality of choice for working up nodules detected at screening, for staging known HCC, and for follow-up. In cirrhotic livers, the combination of tumor arterial phase hyperenhancement plus washout and/or capsular enhancement is highly specific for HCC and can make biopsy unnecessary. Newer imaging techniques may further improve MR imaging sensitivity for HCC and help to characterize tumors with atypical dynamic enhancement patterns.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

