Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

16
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
16
Data Validation01:03

Data Validation

6.4K
Data validation is an essential part of a comprehensive assessment. Validation is confirming or verifying and opening the door to gathering more assessment data as it clarifies vague or unclear data. The process of checking and verifying the collected information is called data validation. The primary purpose of data validation is to ensure data is as free from error, bias, and misinterpretation as possible.
Nursing assessment guides are generally based on holistic models rather than medical...
6.4K
Modeling in Therapy01:26

Modeling in Therapy

811
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
811
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

1.9K
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx).

British journal of clinical pharmacology·2026
Same author

Effectiveness of Guideline-Based Clinical Decision Support Systems: Protocol for a Systematic Review.

JMIR research protocols·2026
Same author

An Event-Condition-Action (ECA)-Based Formalization of Clinical Guidelines.

Studies in health technology and informatics·2026
Same author

Language Models for Automatic Clinical Coding in Veterinary Texts: Experimental Results.

Studies in health technology and informatics·2026
Same author

Standardized Information Model for Clinical Texts: The MII Core Data Set Module Document.

Studies in health technology and informatics·2026
Same author

Data Quality in the ProVal-MS Study: Challenges and Lessons Learned.

Studies in health technology and informatics·2026
Same journal

Classification of periapical radiographic findings for root canal therapy decision support using deep neural networks.

BMC medical informatics and decision making·2026
Same journal

Machine learning-based risk assessment of neonatal perinatal adverse outcomes of anemia during pregnancy: a modeling study.

BMC medical informatics and decision making·2026
Same journal

Intelligent differentiation between Parkinson's disease and essential tremor using wearable sensors and machine learning: a temporal validation study.

BMC medical informatics and decision making·2026
Same journal

Risk prediction of sepsis-associated acute kidney injury: development, validation of a machine learning model with multicenter data.

BMC medical informatics and decision making·2026
Same journal

Trajectory analysis of sleep disorders and anxiety-depression in female breast cancer patients undergoing chemotherapy: based on group-based Multi-Trajectory Model and machine learning.

BMC medical informatics and decision making·2026
Same journal

Multitask learning of longitudinal circulating biomarkers and clinical outcomes: identification of optimal machine-learning and deep-learning models.

BMC medical informatics and decision making·2026
See all related articles

Related Experiment Video

Updated: Apr 26, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.9K

Validating archetypes for the Multiple Sclerosis Functional Composite.

Michael Braun1, Alexander Ulrich Brandt, Stefan Schulz

  • 1Center for Medical Biometry and Medical Informatics, Medical Center - University of Freiburg, Stefan-Meier-Str, 26, 79104 Freiburg, Germany. michael.braun@uniklinik-freiburg.de.

BMC Medical Informatics and Decision Making
|August 4, 2014
PubMed
Summary
This summary is machine-generated.

Developing and validating openEHR archetypes ensures high-quality clinical information models. Community-based review processes, like those in the openEHR Clinical Knowledge Manager, pragmatically harmonize models for better interoperability.

More Related Videos

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

2.6K
A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
07:33

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

Published on: May 21, 2010

35.3K

Related Experiment Videos

Last Updated: Apr 26, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.9K
Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

2.6K
A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
07:33

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

Published on: May 21, 2010

35.3K

Area of Science:

  • Health Informatics
  • Clinical Informatics
  • Information Modeling

Background:

  • Electronic health records rely on robust information models like openEHR archetypes for standardized semantics and interoperability.
  • Current validation methods for clinical models are insufficient, impacting data quality and exchange.
  • Ensuring high-quality information models is critical for effective healthcare data management.

Purpose of the Study:

  • To investigate the feasibility of developing and community-validating openEHR archetypes.
  • To assess the effectiveness of a structured review process for ensuring clinical model quality.
  • To explore how validation can harmonize models and improve data interoperability.

Main Methods:

  • Applied a standard archetype development approach to three multiple sclerosis assessment clinical tests.
  • Organized and structured data elements through iterative refinement.
  • Conducted a formal, community-based review process using the openEHR Clinical Knowledge Manager with clinical and information modeling experts.

Main Results:

  • Successfully developed and deployed four new archetypes on the openEHR Clinical Knowledge Manager.
  • Validated archetypes through a structured team review process, confirming pragmatic validation.
  • Identified development and review as time-consuming, particularly due to selecting modeling approaches.

Conclusions:

  • Community- and tool-enabled review processes, like those in the openEHR Clinical Knowledge Manager, effectively ensure archetype quality.
  • Validation harmonizes models, reducing variation and promoting a more unified, interoperable clinical information landscape.
  • This approach offers a feasible method for enhancing the quality and consistency of electronic health record data.