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A Porcine Model of Acute Autologous Pulmonary Embolism

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Paradoxical embolus in transit.

Berhane Worku¹, Iosif Gulkarov¹, Jeremy Steele²

¹Department of Cardiothoracic Surgery, Weill Cornell Medical College/New York Presbyterian Hospital, New York, New York; Department of Cardiothoracic Surgery, New York Methodist Hospital, New York, New York.

The Annals of Thoracic Surgery

|August 5, 2014

Summary

This summary is machine-generated.

Paradoxical embolus in transit, a clot crossing a patent foramen ovale, signals potential arterial embolism. Early surgical clot removal is recommended for these rare cases.

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Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Vascular Surgery

Background:

A paradoxical embolus in transit occurs when a thrombus (blood clot) straddles a patent foramen ovale (PFO), a hole between the heart's upper chambers.
This rare condition signifies a high risk of arterial embolism, where a clot travels to the arteries.

Observation:

This report details three patients where a paradoxical embolus in transit was identified either before or during surgery.
The embolus was observed straddling the patent foramen ovale in all cases.

Findings:

All three patients underwent surgical evacuation of the thrombus.
Postoperative recovery was uneventful, with no instances of arterial embolization occurring in any patient.

Implications:

Early surgical embolectomy should be strongly considered as a primary treatment strategy for paradoxical embolus in transit.
Prompt intervention can prevent serious complications like stroke or limb ischemia associated with arterial embolism.