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Stay in NICU and infantile haemangioma development
1Department of Dermatology and Pediatric Dermatology; National Centre for Rare Skin Disorders, Hôpital Pellegrin and University of Bordeaux, Inserm U1035, Bordeaux, France.
Insights
Infants requiring neonatal intensive care unit (NICU) admission often present with earlier onset and more extensive infantile haemangiomas (IHs). Early dermatological consultation is crucial for timely diagnosis and treatment of IHs in high-risk infants.
Area of Science:
- Pediatric Dermatology
- Neonatology
- Medical Research
Background:
- Infantile haemangiomas (IHs) are common in premature and low birth weight infants.
- Understanding risk factors associated with IHs in neonatal intensive care unit (NICU) populations is important.
Purpose of the Study:
- To compare the clinical characteristics of infants with IHs who were admitted to the NICU versus those who were not.
- To identify factors associated with NICU hospitalization in infants with IHs.
Main Methods:
- Prospective observational multicentric study.
- Inclusion of consecutive infants presenting with IHs.
- Univariate logistic regression analyses to identify factors associated with NICU hospitalization.
Main Results:
- 210 infants with 323 IHs were analyzed; 27 required NICU admission.
- NICU infants showed higher rates of limb involvement, multiple IHs, and earlier IH onset.
- Congenital onset IHs were more frequent in infants with multiple lesions.
Conclusions:
- Infants admitted to the NICU and those with congenital IHs represent a high-risk group.
- These infants may have specific IH types and involvement patterns.
- Early dermatological evaluation is recommended for suspected IHs in high-risk infants to ensure prompt diagnosis and treatment.
Background:
Infantile haemangiomas (IHs) are more frequent in low birth weight babies, especially premature.
Objective:
To compare the characteristics of infants with IHs who stayed in neonatal intensive care unit (NICU) vs. those with IHs who did not.
Methods:
Prospective observational multicentric study. Consecutive infants consulting for IHs in two departments of paediatric dermatology were included and a questionnaire specifically designed was filled for each patient. To identify factors associated with hospitalization in NICU vs. no hospitalization in NICU, we conducted univariate logistic regression analyses.
Results:
A total of 210 infants with 323 IHs were included (56 boys, 154 girls, F/M sex ratio 2.75/1); 27 stayed in NICU, whereas 183 did not. Limbs involvement and multiple IHs were more frequent in NICU infants. Similarly, infants who had stayed in NICU had an earlier onset of their IH. Multiple IH was more frequent in infants with a history of congenital onset of IH.
Conclusion:
Infants staying in NICU and those with congenital lesion are at risk for specific type and involvement of their IH and should be early addressed to a dermatologist in case of suspicion of IH to provide them an early diagnosis and to start a treatment if necessary as soon as possible.
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