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Updated: Apr 26, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Japodagricanones A and B, novel diterpenoids from Jatropha podagrica
Wei-Wei Liu1, Yu Zhang2, Chun-Mao Yuan2
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China; Gansu Key Laboratory of Crop Improvement and Germplasm Enhancement, Life Science and Technology in the College of Biotechnology, Gansu Agricultural University, Lanzhou 730070, Gansu, PR China.
Abstract:
Two novel diterpenoids, japodagricanones A (1) and B (2), along with their biogenetically related diterpenoid 15-epi-4E-jatrogrossidentadion (3), were isolated from the leaves and twigs of Jatropha podagrica. Japodagricanones A (1) and B (2) are the first C-5-nor lathyrane-type diterpenoids. Their structures were established using spectroscopic data, including MS, NMR and ECD data. A plausible biosynthetic pathway for their generation was also proposed.
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