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Chronic calcifying pancreatitis in children: a report of six cases
F J Penna1, A S Carvalho, M L Roquete
1Departmento de Pediatria, Faculdade de Medicina, Universidade, Federal de Minas Gerais, Belo Horizonte, Brasil.
Insights
Chronic Calcifying Pancreatitis (CCP) affects approximately 1:1,000 pediatric inpatients in Brazil. This study highlights CCP
Area of Science:
- Pediatric Gastroenterology
- Nutritional Science
Background:
- Chronic Calcifying Pancreatitis (CCP) is a rare condition.
- Protein-calorie malnutrition is prevalent in certain pediatric populations.
Purpose of the Study:
- To report the incidence and clinical characteristics of CCP in Brazilian children.
- To explore the potential link between CCP and protein-calorie malnutrition.
- To emphasize the importance of considering CCP in malnourished children unresponsive to standard treatment.
Main Methods:
- Retrospective case series analysis.
- Review of clinical manifestations and therapeutic management.
- Discussion of potential etiological factors.
Main Results:
- Six cases of CCP were identified over a 10-year period.
- Incidence rate approximated 1:1,000 pediatric inpatients.
- Clinical features and treatment outcomes were documented.
Conclusions:
- CCP may be associated with primary protein-calorie malnutrition in children.
- Early diagnosis of CCP is crucial for effective management in malnourished pediatric patients.
- Further research is warranted to elucidate the pathophysiology and optimize treatment strategies.
Abstract:
1. A study of six patients with Chronic Calcifying Pancreatitis (CCP) occurring over a 10 year period, representing an incidence rate of approximately 1:1,000 of the inpatients in the children's ward of a general hospital in central Brazil, is reported. 2. Major clinical manifestations as well as therapeutic management are described. 3. The possible relationship between CCP and primary protein-calorie malnutrition is discussed and the importance of a CCP diagnosis when dealing with malnourished children who do not respond satisfactorily to common therapy is emphasized.