Related Experiment Video
Updated: Apr 26, 2026

07:44
Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
Published on: May 12, 2023
2.1K
Vaccination in humanitarian crises: satisficing should no longer suffice
Rebecca F Grais1, Aitana Juan-Giner2
1Epicentre, 8 rue Saint Sabin, Paris 75011, France rebecca.grais@epicentre.msf.org.
International Health
|August 6, 2014
Summary
Delivering vaccines during crises is challenging due to limited data and logistical issues. More effectiveness studies are needed to improve vaccination intervention decisions in humanitarian emergencies.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- Numerous vaccination interventions exist to mitigate health risks in crisis-affected populations.
- However, delivering these vaccines effectively in crisis settings presents significant challenges.
Purpose of the Study:
- To examine the difficulties and factors influencing the implementation of vaccination interventions in crisis situations.
- To highlight the need for improved decision-making processes based on robust data.
Main Methods:
- Review of existing literature on vaccine delivery in crises.
- Analysis of factors affecting decision-making, including data availability, vaccine characteristics, and political considerations.
Main Results:
- Decision-making for vaccination in crises often relies on 'satisficing' due to sparse epidemiologic and effectiveness data.
- Limitations in vaccine presentation, formulation, storage, political factors, and lack of guidance exacerbate implementation difficulties.
Conclusions:
- Effective implementation of vaccination interventions in crises is hampered by data scarcity and logistical constraints.
- Future efforts must prioritize sound effectiveness studies to ensure evidence-based decision-making in humanitarian settings.
More Related Videos
Related Concept Videos
Vaccinations
43.8K
Overview
43.8K
Vaccines
86
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
86
Cross-reactivity
28.7K
Overview
28.7K
Vaccine Production
129
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
129
Cancer Vaccines
1.3K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.3K
Microorganisms in Medicine and Therapeutics
1.3K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K

