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Inflammatory bowel disease in a child with sickle cell anemia

Khaled Alqoaer1, Mohammed M Ahmed1, Efteraj S Alhowaiti1

  • 1Pediatric Department, Prince Salman North West Armed Forces Hospital, P.O. Box 100, Tabuk 71411, Saudi Arabia.

Case Reports in Pediatrics
|August 6, 2014
PubMed

Insights

Sickle cell anemia (SCA) rarely affects the colon, typically as ischemic colitis. This case highlights a rare instance of inflammatory bowel disease presenting in a child with SCA.

Area of Science:

  • Gastroenterology
  • Hematology
  • Pediatrics

Background:

  • Sickle cell anemia (SCA) is a genetic blood disorder affecting multiple organs.
  • Gastrointestinal complications of SCA are common, but colonic involvement is infrequent.
  • Ischemic colitis is the most recognized colonic manifestation of SCA.

Purpose of the Study:

  • To report a rare case of inflammatory bowel disease (IBD) in a pediatric patient with SCA.
  • To emphasize the atypical gastrointestinal presentations of SCA.
  • To contribute to the understanding of SCA's diverse organ involvement.

Main Methods:

  • Case report of an 11-year-old Saudi girl with SCA.
  • Clinical presentation of persistent diarrhea.
  • Diagnostic workup for gastrointestinal pathology.

Main Results:

  • The patient, diagnosed with SCA, presented with chronic diarrhea.
  • Investigations revealed inflammatory bowel disease, not ischemic colitis.
  • This represents an unusual colonic manifestation in SCA.

Conclusions:

  • Inflammatory bowel disease is a rare but possible gastrointestinal complication in sickle cell anemia.
  • Atypical presentations of SCA require thorough investigation.
  • This case expands the spectrum of known SCA-related colonic pathologies.

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