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The endogenous pyrogens in host-defense interactions
1Tufts University School of Medicine, Boston.
Hospital Practice (Office Ed.)
|November 15, 1989
Abstract:
Soluble factors produced by activated macrophages serve to marshal host defenses against infection, injury, or inflammation, but they may also cause chronic inflammation or even lethal shock. Suppressing or enhancing such cytokine functions has important therapeutic potential in, respectively, chronic inflammatory and immunologically deficient states.