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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
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Headache and acute stroke.
Dara G Jamieson1, Natalie T Cheng, Maryna Skliut
1Weill Cornell Medical College, New York Presbyterian Hospital, 428 East 72nd Street, Suite 400, New York, NY, 10021, USA, dgj2001@med.cornell.edu.
Current Pain and Headache Reports
|August 7, 2014
Summary
Prominent headaches, including migraine with aura, are linked to increased stroke risk. Certain neurological disorders and pregnancy also raise the risk of both ischemic and hemorrhagic stroke.
Area of Science:
- Neurology
- Vascular Neurology
- Neurocritical Care
Background:
- Prominent headaches, such as migraine with aura, are associated with increased risks of ischemic and hemorrhagic stroke.
- Several neurological disorders, including central nervous system vasculitis, posterior reversible encephalopathy syndrome, reversible cerebral vasoconstriction syndrome, and cerebral venous thrombosis, present with severe headaches and elevate stroke risk.
- Pregnancy and the postpartum period represent a critical time for the overlap of new-onset headaches and heightened stroke risk.
Purpose of the Study:
- To review the association between headache disorders and stroke risk.
- To highlight specific neurological conditions that increase the risk of both ischemic and hemorrhagic stroke.
- To emphasize the heightened stroke risk during pregnancy and postpartum, particularly in the context of new-onset headaches.
Main Methods:
- Literature review of studies investigating headache disorders and stroke.
- Analysis of clinical presentations of stroke, differentiating between ischemic and hemorrhagic types.
- Examination of risk factors for stroke, including specific neurological syndromes and the peripartum period.
Main Results:
- Migraine with aura and cerebral arterial and venous diseases are identified as conditions increasing stroke risk.
- Central nervous system vasculitis, posterior reversible encephalopathy syndrome, reversible cerebral vasoconstriction syndrome, and cerebral venous thrombosis are linked to increased risk of ischemic and hemorrhagic stroke.
- Hemorrhagic strokes are more frequently associated with distinct headaches and focal neurological symptoms compared to ischemic strokes.
Conclusions:
- Disorders causing prominent headaches significantly increase the risk of stroke.
- Early recognition and management of these headache disorders and associated neurological conditions are crucial for stroke prevention.
- The peripartum period requires careful consideration of headache symptoms as potential indicators of increased stroke risk.
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