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Updated: Apr 26, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
[Hepatitis C infection in children]
Vibeke Brix Christensen1, Sannie Nordly, Bjørn Fischler
1Gl. Strandvej 97, 3050 Humlebæk. brixchr@dadlnet.dk.
Abstract:
Chronic hepatitis C (HCV) infection has a prevalence of 2-3% worldwide. The vertical transmission rate is approximately 5%. There is no evidence to recommend abstinence from breastfeeding or elective C-section to prevent transmission. In children, the natural history of HCV infection is typically benign, but liver cirrhosis and hepatocellulary carcinoma are later complications. Children with HCV infection may benefit from early treatment with pegylated interferon and ribavirin with duration depending on genotype. Overall, response to antiviral treatment of HCV infected children is comparable to results in adults.
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