Related Experiment Video
Updated: Apr 26, 2026
06:53
Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
15.5K
[Basal cell carcinoma and rare form variants]
1Dermatopathologie Duisburg, An der Abtei 7-11, 47166, Duisburg, Deutschland.
Der Pathologe
|August 7, 2014
Summary
Basal cell carcinoma, the most common skin cancer, presents diverse subtypes. This review details their clinical and histopathological features, aiding accurate diagnosis for pathologists and dermatopathologists.
Area of Science:
- Dermatopathology
- Oncology
- Histopathology
Context:
- Basal cell carcinoma (BCC) is the most frequent primary malignant neoplasm of the skin.
- Accurate diagnosis of BCC is a routine yet critical task for pathologists and dermatopathologists.
- Understanding BCC subtypes is essential for effective patient management and treatment planning.
Purpose:
- To provide a comprehensive overview of the clinical and histopathological characteristics of common basal cell carcinoma subtypes.
- To discuss rare variants of basal cell carcinoma, enhancing diagnostic capabilities.
- To clarify the differential diagnoses for various basal cell carcinoma presentations.
Summary:
- This review focuses on the clinical and histopathological presentation of common basal cell carcinoma (BCC) subtypes.
- It also addresses rare BCC variants and their differential diagnoses, offering valuable insights for diagnostic accuracy.
- The content is geared towards pathologists and dermatopathologists involved in routine BCC diagnosis.
Impact:
- Enhances the diagnostic accuracy of basal cell carcinoma (BCC) for pathologists and dermatopathologists.
- Provides a consolidated resource for understanding the spectrum of BCC subtypes and rare variants.
- Aids in differentiating BCC from other cutaneous neoplasms, improving patient care and outcomes.
More Related Videos
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
2.8K
06:09Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
Published on: June 7, 2019
8.6K
Related Concept Videos
01:30Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
02:21Cancers Originate from Somatic Mutations in a Single Cell
12.4K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
12.4K
02:21Cancers Originate from Somatic Mutations in a Single Cell
3.1K
3.1K
01:20The Retinoblastoma Gene
3.7K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
3.7K
02:23Abnormal Proliferation
4.0K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.0K
02:40Cancer Stem Cells and Tumor Maintenance
4.3K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
4.3K