Related Experiment Video
Updated: Apr 26, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Stevens-Johnson syndrome/toxic epidermal necrolysis presumably induced by norfloxacin
Jolanta Maciejewska1, Marek Jankowski1, Barbara Zegarska2
1Department of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Ludwik Rydygier Medical College in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland. Head of Department: Rafał Czajkowski MD, PhD, DSc, Assoc. Prof.
Abstract:
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare mucocutaneous, unpredictable, life-threatening drug side reactions. A very rare case of norfloxacin-induced SJS/TEN overlap with uncommon clinical presentation in a patient with a suspected urinary tract infection is reported. The SJS/TEN management with possible treatment capabilities are discussed. In spite of only two previous reports of norfloxacin-induced SJS and TEN we believe that awareness of norfloxacin adverse reactions needs to be raised among prescribers.
More Related Videos
Related Concept Videos
Drug Toxicity: Allergic Reactions
Inhibitors of Bacterial DNA Synthesis
Drug toxicity: Idiosyncratic Reactions
Drug Toxicity: Dose-Dependent Reactions
Staphylococcal Skin Infections
Drug Toxicity: Risk factors

