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[Anti-N-Methyl-D-aspartate receptor encephalitis (anti-NMDAR): a case report]

Paulina González-Latapi1, Mayela Rodríguez-Violante2, Amin Cervantes-Arriaga1

  • 1Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, México, D.F.

Gaceta Medica De Mexico
|August 8, 2014
PubMed

Insights

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune disease. This case report details the first confirmed instance in Mexico of anti-NMDAR encephalitis in a teenager without a neoplasm.

Area of Science:

  • Neurology
  • Immunology
  • Autoimmune Disorders

Background:

  • Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a significant cause of noninfectious encephalitis.
  • It presents with diverse neuropsychiatric symptoms, movement disorders, and autonomic dysfunction.

Observation:

  • A case study of a 16-year-old male diagnosed with anti-NMDAR encephalitis is presented.
  • The diagnosis was confirmed by the presence of anti-NMDAR antibodies.
  • No associated neoplasm was identified in this patient.

Findings:

  • The patient experienced a gradual recovery following diagnosis.
  • This represents the first documented case of anti-NMDAR encephalitis in Mexico.

Implications:

  • Highlights the importance of recognizing anti-NMDAR encephalitis in adolescents presenting with neurological and psychiatric symptoms.
  • Emphasizes that anti-NMDAR encephalitis can occur in the absence of malignancy.
  • Contributes to the understanding of the geographical distribution and clinical presentation of this autoimmune disorder.

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