Related Experiment Videos
Induction of the SOS response in Escherichia coli by heavy ions
S Kozubek1, E A Krasavin, I Soska
1Joint Institute for Nuclear Research, Dubna, U.S.S.R.
Mutation Research
|November 1, 1989
Abstract:
The effectiveness of heavy ions in inducing the SOS response in E. coli cells has been measured by means of the SOS-chromotest. The SOS induction potency of ionizing radiation increases with increasing LET, to 40-60 keV/microns, reaches a maximum and then decreases at greater LET values. We conclude that the SOS-inducing damages in the case of ionizing radiation could be DNA injuries of a 'complex' type, e.g., DNA double-strand breaks or some kind of heavily damaged single-strand lesions.