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Updated: Apr 26, 2026

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Real-time Imaging of Myeloid Cells Dynamics in ApcMin/+ Intestinal Tumors by Spinning Disk Confocal Microscopy
Published on: October 6, 2014
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[A case of multiple primary small intestinal adenocarcinomas]
Masafumi Yoshioka1, Seiichi Shinji, Hayato Kan
1Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School.
Summary
This case highlights multiple primary small intestinal cancers in a patient with stenoses. Early diagnosis of primary small intestinal cancer is crucial for effective treatment.
Area of Science:
- Gastroenterology
- Oncology
Background:
- Non-steroidal anti-inflammatory drug (NSAID) use and gastric ulcers are known risk factors for gastrointestinal issues.
- Intestinal obstruction can be a symptom of various underlying pathologies.
Observation:
- A 62-year-old woman presented with intestinal obstruction due to two stenoses and ulcers in the ileum.
- Histological examination revealed poorly differentiated adenocarcinomas in both stenotic lesions.
Findings:
- Despite initial suspicion of metastatic cancer, whole-body examination ruled out other lesions.
- The final diagnosis was multiple primary small intestinal malignancies, requiring further surgical intervention.
Implications:
- This case underscores the importance of considering primary small intestinal cancer in patients presenting with multiple small intestinal stenoses.
- Increased physician awareness can lead to earlier diagnosis and improved patient outcomes for this rare malignancy.
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