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Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...

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Related Experiment Video

Updated: Apr 26, 2026

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue

Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue

Published on: April 6, 2022

Airway tissue engineering: an update.

Jonathan M Fishman¹, Katherine Wiles, Mark W Lowdell

¹UCL Institute of Child Health, Department of Surgery , 30 Guilford Street, London WC1N 1EH , UK +44 07989 331573 ; j.fishman@ucl.ac.uk.

Expert Opinion on Biological Therapy

|August 8, 2014

Summary

This summary is machine-generated.

Tissue engineering and regenerative medicine offer new hope for airway reconstruction. Stem cell-based therapies show promise for tracheal transplants, potentially eliminating the need for immunosuppression.

Keywords:

airway management angiogenesis artificial organs biocompatible materials bioreactors larynx regenerative medicine stem cells tissue engineering tissue scaffolds trachea transplantation

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Last Updated: Apr 26, 2026

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Area of Science:

Regenerative medicine
Tissue engineering
Stem cell biology

Background:

Traditional methods like prosthetics and homografts fail for extensive airway damage.
Research focuses on stem cell-based constructs for airway repair and regeneration.

Purpose of the Study:

To summarize progress in tissue-engineered airways.
To outline current research questions and future directions.

Main Methods:

Advances in stem cell technology, biomaterials, and growth factors.
Development of tissue-engineered airways for clinical trials.
Investigating decellularization techniques and transplantation immunobiology.

Main Results:

First-in-man studies for stem cell-based tracheal transplants are underway.
Understanding of immune interactions in transplantation is improving.
Progress in airway revascularization, reinnervation, and bioreactor design.

Conclusions:

Tissue-engineered airways may eliminate lifelong immunosuppression.
New avenues for tissue-engineered larynx construction are emerging.
3D printing offers precise control over cell incorporation in airway engineering.