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A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
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Computational analysis of functional single nucleotide polymorphisms associated with the CYP11B2 gene

Minyue Jia1, Boyun Yang1, Zhongyi Li2

  • 1Department of Endocrinology and Metabolism, the Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.

Plos One
|August 8, 2014
PubMed
Summary

This study computationally identified four harmful single nucleotide polymorphisms (SNPs) in the CYP11B2 gene that affect protein function and stability. It also found three 3'UTR SNPs impacting microRNA binding, crucial for genetic studies.

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