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Updated: Apr 26, 2026

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
Published on: May 18, 2021
The linkage between psoriasis and non-alcoholic fatty liver disease: a literature review
Andréia Nogueira Ramos, Bruno de Oliveira Rocha, Vitória Regina Pedreira de Almeida Rêgo
1Maria de Fátima Santos Paim de Oliveira, MD, MSc, PhD, Artesão João da Prata Street, 267, Room 602, Itaigara, Salvador, Bahia, Brazil; mfatimapaim@gmail.com.
Abstract:
Psoriasis is a chronic systemic inflammatory disease mainly affecting the skin. Population-based surveys have shown a higher prevalence of non-alcoholic fat liver disease (NAFLD) in patients with psoriasis compared with the general population, especially in those with a greater psoriasis area and severity index (PASI). It is speculated that similar pathogenic bases may play a role in this association, highlighting insulin resistance and the release of inflammatory cytokines as the most likely causes. In the present work, we review basic aspects of the relationship between psoriasis and NAFLD.
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