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The discovery of beta-galactosidase
Trends in Biochemical Sciences
|October 1, 1989
Summary
A 90-year-old lactase preparation, discovered in a historical collection, still shows measurable enzyme activity. This finding highlights the enduring nature of enzyme preparations even after decades of suboptimal storage.
Area of Science:
- Enzymology
- Microbiology
- Biochemistry
Background:
- The enzyme beta-galactosidase, also known as lactase, was first documented by Beijerinck.
- The Delft University of Technology maintains a historical collection preserving Beijerinck's legacy.
Observation:
- A 90-year-old lactase preparation was recently discovered in the 'Beijerinck-room'.
- The preparation was stored under suboptimal conditions for nine decades.
Findings:
- Despite prolonged and inadequate storage, the ancient lactase preparation retained measurable enzyme activity.
- This indicates remarkable stability of the enzyme preparation over time.
Implications:
- Historical enzyme preparations can remain viable for extended periods.
- This discovery has implications for understanding enzyme stability and historical biochemical research.