Imaging findings of thyroidal sarcoma
Related Experiment Video
Updated: Apr 26, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Alexey Surov1, Hans Jürgen Holzhausen2, Andreas Machens3
1Department of Radiology, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Abstract:
From 1997 to 2013, 8849 patients with several disorders of the thyroid were treated in our surgical department. In nine patients (0.1%), primary thyroid sarcoma (PTS) was diagnosed. In eight patients, PTS manifested as a thyroid mass (range, 25-90 mm). In one case, a global enlargement of the thyroid was seen. Clinically, all patients presented with neck swelling. On ultrasound, PTS was predominantly hypoechoic. On computed tomography, the sarcomas were hypodense. On magnetic resonance imaging, PTS had inhomogeneous signal increase on T2-weighted images and signal decrease on T1-weighted images with inhomogeneous enhancement.
Related Concept Videos
Graves Disease II: Pathophysiology
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

