Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

5.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
5.2K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.5K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.5K
Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

15
Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
15
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

8.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
8.4K
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

18
Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH...
18
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

23
Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
23

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contralateral prophylactic mastectomy in a rural population: A single-institution experience.

Surgery open science·2024
Same author

Differences in Distress Between Rural and Non-rural Appalachian Breast Cancer Patient/Caregiver Dyads During the First Year of Treatment.

Journal of Appalachian health·2023
Same author

The Development of Breast Cancer-Related Lymphedema After Mastectomy in a Rural Population.

The American surgeon·2023
Same author

A pro-inflammatory and fibrous cap thinning transcriptome profile accompanies carotid plaque rupture leading to stroke.

Scientific reports·2022
Same author

Lessons Learned From an Early Hotspot During the COVID-19 Pandemic.

The American surgeon·2021
Same author

Factors That Predict Biological Aggressiveness in Estrogen Receptor-Positive / Human Epidermal Growth Factor Receptor 2-Negative / Lymph Node-Negative Breast Cancer.

Ochsner journal·2021

Related Experiment Video

Updated: Apr 26, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.5K

Parathyroid hormone levels predict posttotal thyroidectomy hypoparathyroidism.

Amy E Rivere1, Ashton J Brooks, Genevieve A Hayek

  • 1Department of Surgery, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

The American Surgeon
|August 9, 2014
PubMed
Summary
This summary is machine-generated.

Post-thyroidectomy hypoparathyroidism is best identified using parathyroid hormone (PTH) levels. Early PTH measurement after total thyroidectomy enables prompt management and improved patient outcomes.

More Related Videos

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.7K
Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
07:13

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017

17.1K

Related Experiment Videos

Last Updated: Apr 26, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.5K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.7K
Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
07:13

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017

17.1K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Neurosurgery

Background:

  • Post-thyroidectomy hypoparathyroidism (PTTHP) is a common complication following total thyroidectomy.
  • Accurate and timely diagnosis of PTTHP is crucial for effective management and patient outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of parathyroid hormone (PTH) determination in identifying PTTHP compared to other clinical and laboratory parameters.
  • To establish a reliable diagnostic threshold for PTH in predicting PTTHP.

Main Methods:

  • Retrospective review of 202 total thyroidectomy cases (October 2010 - June 2013).
  • Data collected included demographics, malignancy, thyroid weight, parathyroid autotransplantation, hospital stay, and postoperative calcium and PTH levels.
  • Patients were categorized based on the need for calcitriol supplementation to maintain eucalcemia, defining PTTHP.

Main Results:

  • Twenty-four patients (12%) developed PTTHP requiring calcitriol.
  • Postoperative PTH levels (P < 0.0001) and calcium levels (P = 0.02) were significant predictors of PTTHP.
  • A PTH level of 13 pg/mL or less accurately predicted PTTHP (22/29 patients), while levels above 13 pg/mL rarely indicated PTTHP (2/173 patients).

Conclusions:

  • Postoperative PTH level determination is the most effective strategy for identifying patients with PTTHP.
  • An early PTH measurement can facilitate prompt management, potentially shortening hospital stays and improving outcomes.