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Updated: Apr 26, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Alteplase in acute ischaemic stroke: the need for speed
Michael D Hill1, Shelagh B Coutts2
1Department of Clinical Neuroscience, University of Calgary, Calgary, AB T2N 2T9, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Medicine, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 2T9, Canada; Department of Radiology, University of Calgary, Calgary, AB T2N 2T9, Canada.
No abstract available in PubMed .
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As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...

