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Related Experiment Videos

The Yale-Brown Obsessive Compulsive Scale. II. Validity.

W K Goodman1, L H Price, S A Rasmussen

  • 1Department of Psychiatry, Yale University School of Medicine, New Haven 06508.

Archives of General Psychiatry
|November 1, 1989
PubMed
Summary
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The Yale-Brown Obsessive Compulsive Scale is a valid and reliable tool for measuring obsessive-compulsive disorder (OCD) symptom severity. This scale effectively tracks symptom changes, making it suitable for clinical trials evaluating OCD treatments.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Pharmacology

Background:

  • The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is a widely used instrument for assessing obsessive-compulsive disorder (OCD).
  • Previous work has established the development, design, and reliability of the Y-BOCS.
  • This study specifically investigates the validity and sensitivity to change of the Y-BOCS.

Purpose of the Study:

  • To evaluate the convergent and discriminant validity of the Y-BOCS in patients with OCD.
  • To assess the Y-BOCS's sensitivity to therapeutic changes in OCD symptom severity.
  • To confirm the Y-BOCS's suitability as an outcome measure in pharmacological trials for OCD.

Main Methods:

  • Examined convergent and discriminant validity using baseline ratings from three cohorts of patients with OCD (N=81).

Related Experiment Videos

  • Correlated total Y-BOCS scores with independent OCD measures, depression, and anxiety measures.
  • Analyzed data from a placebo-controlled trial of fluvoxamine (N=42) to assess Y-BOCS sensitivity to drug-induced changes.

    • Main Results:

    • The total Y-BOCS score showed significant correlations with two of three independent OCD measures.
    • Y-BOCS scores exhibited weak correlations with depression and anxiety measures in patients with minimal secondary depressive symptoms.
    • The Y-BOCS demonstrated sensitivity to drug-induced changes, with score reductions reflecting specific improvements in OCD symptoms.

    Conclusions:

    • The 10-item Yale-Brown Obsessive Compulsive Scale is a reliable and valid instrument for assessing OCD symptom severity.
    • The Y-BOCS is suitable for use as an outcome measure in drug trials for obsessive-compulsive disorder.
    • The findings support the continued use of the Y-BOCS in clinical research and practice for OCD.