Related Experiment Video
Updated: Apr 26, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Is pressure-regulated volume control mode appropriate for severely obstructed patients?
Alberto Medina1, Vicent Modesto-Alapont2, Carlos Lobete1
1Paediatric Intensive Care Unit, Hospital Universitario Central de Asturias, University of Oviedo, Oviedo, Spain.
Purpose:
Management of mechanical ventilation in severely obstructed patients remains controversial. Pressure-regulated volume control ventilation (PRVCV) has been suggested to be the best option, as it should ensure a prefixed tidal volume at the lowest peak inspiratory pressure. We sought to determine the accuracy of the delivered volume, compared with the programmed volume, when using PRVCV.
Materials And Methods:
Experimental work performing ventilation simulations using volume control ventilation (VCV), PRVCV, and pressure control ventilation (PCV). Each mode was tested at tidal volumes (TVs) of 200 and 500 mL at both low and high airway resistance. Evita XL and Servo-i ventilators were used.
Results:
At 200 ml TV with high resistance, volume delivered with Evita XL was 165 mL (95% confidence interval, 158-169) in VCV, 117 mL (95% confidence interval, 117-120) in PCV, and 120 (95% confidence interval, 115-121) in PRVCV (P<.001). Volume delivered with Servo-i was 133 mL (95% confidence interval, 130-136) in VCV, 108 mL (95% confidence interval, 104-111) in PCV, and 104 (95% confidence interval, 101-108) in PRVCV (P<.001).
Conclusions:
In high-resistance simulations, the delivered volume was lower when using PCV or PRVCV modes than VCV mode. Pressure control ventilation or PRVCV may fail to provide programmed TV, ultimately leading to hypoventilation of the patient.
More Related Videos
04:16Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
Published on: January 30, 2026
09:31Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Related Concept Videos
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Cardiopulmonary Resuscitation II: ACLS Airway Management
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...