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Recurrent arterial and venous thromboemboli as initial presentation of acute promyelocytic leukemia
Felix Trottier-Tellier1, Madeleine Durand2, Christophe Kolan3
1Universite de Montreal, Montreal, Canada.
Abstract:
We report a case of a 52-year-old Caucasian woman diagnosed with a synchronic arterial and venous thrombosis as an initial presentation of an acute promyelocytic leukemia (APL). After the diagnosis, the patient was treated with all trans-retinoic acid and arsenic chemotherapy concomitant to systemic anticoagulation. This treatment regimen led to a complete remission and absence of relapse of the thrombosis or APL during the follow-up. To our knowledge, this presentation is the second case in the literature. We use this opportunity to emphasize the importance of performing a complete medical evaluation in cases of unusual thromboembolic events.
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