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Updated: Apr 26, 2026

Transcranial Pulse Stimulation for Alzheimer's Patients
Published on: April 4, 2025
A rehabilitation program for Alzheimer's disease.
Bernat-Carles Serdà i Ferrer1, Arantza del Valle
11PhD, Lecturer, Department of Nursing, and Researcher, Biomedical Research Institute, University of Girona, Catolonia, Spain 2PhD, Lecturer, Psychology Department, University of Girona, Catolonia, Spain.
This rehabilitation program (RP) improved physical fitness and quality of life in Alzheimer's disease patients. Cognitive abilities did not show significant improvement.
Area of Science:
- Gerontology
- Neurorehabilitation
- Geriatric Medicine
Background:
- A tailored rehabilitation program (RP) was developed for Alzheimer's disease (AD) patients.
- The RP incorporates aerobic, resistance, and balance exercises based on American College of Sports Medicine guidelines.
Purpose of the Study:
- To assess the impact of the RP on physical and functional capacities.
- To evaluate the RP's effect on cognitive functions and quality of life (QOL) in AD patients.
Main Methods:
- A 12-month quasiexperimental study involving 64 participants with AD.
- Assessed cognitive ability (MMSE), fitness (Chair Stand Test), independence (Barthel Index), and QOL (SF-12).
- Statistical analysis included t-tests, Mann-Whitney U, and chi-squared tests.
Main Results:
- The RP demonstrated effectiveness in enhancing physical fitness among participants.
- Significant improvements were observed in the quality of life for individuals with mild-to-moderate AD.
Conclusions:
- The RP positively influences physical capacity and QOL in mild-to-moderate AD patients.
- No significant impact was found on cognitive abilities.
- RP serves as a valuable complementary therapy for AD management, benefiting patients and caregivers.
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