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Stroke code improves intravenous thrombolysis administration in acute ischemic stroke.

Chih-Hao Chen1, Sung-Chun Tang2, Li-Kai Tsai2

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Implementing a Stroke Code protocol significantly increased the administration of intravenous thrombolysis for acute ischemic stroke patients. This initiative also reduced the critical door-to-needle time, improving stroke care efficiency.

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Area of Science:

  • Neurology
  • Emergency Medicine
  • Cardiovascular Research

Background:

  • Timely intravenous thrombolysis is crucial for acute ischemic stroke outcomes.
  • Stroke Code protocols may enhance the administration of IV tissue plasminogen activator (tPA).

Purpose of the Study:

  • To evaluate the impact of a Stroke Code protocol on IV thrombolysis rates and efficiency in acute ischemic stroke patients.

Main Methods:

  • A comparative study divided into pre-Stroke Code (2006-2010) and Stroke Code (2010-2013) eras.
  • Demographics, critical time intervals, stroke severity, and outcomes were analyzed.
  • IV-tPA administration rates and door-to-needle times were compared between eras.

Main Results:

  • IV-tPA administration for eligible patients increased from 13.9% to 33.3% after Stroke Code implementation (P<0.001).
  • Median door-to-needle time decreased significantly from 88 to 51 minutes (P<0.001).
  • The percentage of patients receiving IV-tPA within 60 minutes improved from 14.3% to 71.3%.

Conclusions:

  • The Stroke Code protocol effectively increases IV-tPA administration for acute ischemic stroke.
  • This protocol significantly reduces door-to-needle time, enhancing the speed of stroke treatment.