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[Does parenteral fat administration modify immunocompetence?]
P Thul1, J M Müller, H W Keller
1Chirurgische Universitätsklinik Köln-Lindenthal.
Evidence from studies in carcinoma patients who received intravenous glucose or glucose-lipid solutions preoperatively indicates that fibrinogen, alpha-II-macroglobulin, and coeruloplasmin serum levels remain unchanged. On the other hand, parenteral administration of lipids or glucose induces an increase of IgM, IgG, IgA and complement C3 serum concentrations. Cutaneous allergy testing shows no significant difference whether only glucose was used or half of the calories were replaced by 2.4 g lipids/kg BW x day.
Evidence from studies in carcinoma patients who received intravenous glucose or glucose-lipid solutions preoperatively indicates that fibrinogen, alpha-II-macroglobulin, and coeruloplasmin serum levels remain unchanged. On the other hand, parenteral administration of lipids or glucose induces an increase of IgM, IgG, IgA and complement C3 serum concentrations. Cutaneous allergy testing shows no significant difference whether only glucose was used or half of the calories were replaced by 2.4 g lipids/kg BW x day.