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Protein S-glutathionylation: from current basics to targeted modifications

Doina Popov1

  • 1Institute of Cellular Biology and Pathology "N. Simionescu" of the Romanian Academy , 8, B.P. Hasdeu Street, Bucharest 050568 , Romania.

Archives of Physiology and Biochemistry
|August 13, 2014
PubMed
Summary

Protein S-glutathionylation, a reversible modification, protects cells from oxidative stress. This redox switch regulates cell survival and death, offering potential therapeutic strategies for cardiovascular diseases.

Keywords:
Cysteineglutaredoxinglutathioneprotein tyrosine phosphatases (PTPs)thioredoxin

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