Retinal vein thrombosis in a patient with pernicious anemia and anticardiolipin antibodies

P S Heckerling1, C J Froelich, S G Schade

  • 1Department of Medicine, University of Illinois, Chicago 60680.

A 45-year-old man with pernicious anemia presented with sudden loss of vision due to central retinal vein thrombosis, and was found to have anticardiolipin antibodies and a clotting disorder consistent with the presence of a lupus anticoagulant. He was treated with low dose aspirin and has remained free of recurrent thrombosis over a period of one year. The association between lupus anticoagulant and pernicious anemia is rare, having been reported in only one prior case.