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Updated: Apr 26, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Posterior leaflet segment 2 plication in ischemic mitral regurgitation repair
Yasin Ay1, Alper Erkin2, Ibrahim Kara3
1Department of Cardiovascular Surgery, Bezmialem Vakif University, Istanbul, Turkey.
Aim:
To evaluate the medium-term results of plication of posterior leaflet segment 2 in addition to ring annuloplasty in patients with functional ischemic mitral regurgitation.
Methods:
The study included 136 patients who underwent mitral valve repair with plication of posterior leaflet segment 2 for ischemic mitral regurgitation between 2004 and 2012. The direction and correlation of left ventricle sphericity and tethering area were established by Pearson correlation analysis in patients with or without recurrent mitral regurgitation in the medium term.
Results:
Medium-term survival was 91.9% and freedom from moderate or severe mitral regurgitation was 89.6%. In medium-term follow-up, transthoracic echocardiography found a significant decrease in tethering area, coaptation height, and distance between the commissures compared to the pre-surgery values (p = 0.0001 in all). The distance between the papillary muscles was reduced compared to the pre-surgery period but it was not significant (p = 0.204). Pearson correlation analysis found no significant correlation between the tethering area and left ventricle sphericity in patients without recurrent mitral regurgitation (r = 0.15, p = 0.36), a highly positive correlation (r = 0.44, p < 0.001) in patients with mild recurrent mitral regurgitation, and a moderately positive correlation (r = 0.71, p < 0.01) in patients with moderate or severe recurrent mitral regurgitation.
Conclusions:
The tethering area, coaptation height, and distance between the commissures decreased significantly, thus posterior leaflet segment 2 plication in addition to ring annuloplasty may be the optional procedure to ensure freedom from moderate or severe mitral regurgitation.
Insights
Plication of posterior leaflet segment 2 with ring annuloplasty significantly reduced mitral regurgitation and improved heart function in patients with ischemic mitral regurgitation. This surgical approach offers a promising option for managing this condition.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Mitral Valve Repair
Background:
- Functional ischemic mitral regurgitation (FIMR) is a common complication of myocardial infarction.
- Current surgical options for FIMR include mitral valve repair and replacement, with varying outcomes.
- Plication of posterior leaflet segment 2 is a technique used in mitral valve repair.
Purpose of the Study:
- To evaluate the medium-term results of posterior leaflet segment 2 plication combined with ring annuloplasty in patients with FIMR.
- To assess the impact of this combined surgical approach on mitral regurgitation severity and left ventricular geometry.
Main Methods:
- A retrospective study of 136 patients who underwent mitral valve repair for FIMR between 2004 and 2012.
- Surgical technique involved plication of posterior leaflet segment 2 and ring annuloplasty.
- Pearson correlation analysis was used to assess the relationship between left ventricle sphericity and tethering area in patients with and without recurrent mitral regurgitation.
Main Results:
- Medium-term survival was 91.9%, and freedom from moderate or severe mitral regurgitation was 89.6%.
- Transthoracic echocardiography showed significant reductions in tethering area, coaptation height, and intercommissural distance post-surgery (p < 0.0001).
- A positive correlation was observed between tethering area and left ventricle sphericity in patients with recurrent mitral regurgitation.
Conclusions:
- Posterior leaflet segment 2 plication combined with ring annuloplasty is an effective procedure for FIMR.
- The technique leads to significant improvements in mitral valve geometry and reduces regurgitation severity.
- This approach may be an optional procedure to ensure freedom from moderate or severe mitral regurgitation.
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