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Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
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Bone marrow lesions: A systematic diagnostic approach.

Filippo Del Grande1, Sahar J Farahani1, John A Carrino1

  • 1The Russell H. Morgan Departments of Radiology and Radiology Science, Johns Hopkins Hospital, Baltimore, MD 21287, USA.

The Indian Journal of Radiology & Imaging
|August 13, 2014
PubMed
Summary

Magnetic resonance imaging (MRI) can detect bone marrow lesions from various causes. This study provides a systematic approach to diagnose these lesions using advanced MRI techniques for accurate identification.

Keywords:
Bone marrow lesionchemical shift imagingdiffusionmagnetic resonance imaging

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Area of Science:

  • Radiology
  • Medical Imaging
  • Oncology

Background:

  • Bone marrow lesions are frequently observed in magnetic resonance (MR) imaging.
  • These lesions can be indicative of a wide range of underlying pathologies.

Purpose of the Study:

  • To present a systematic diagnostic strategy for bone marrow lesions.
  • To categorize the diverse etiologies of bone marrow lesions.

Main Methods:

  • Utilizing characteristic imaging features on conventional MR imaging.
  • Employing advanced MR techniques, including chemical shift imaging and diffusion-weighted imaging (DWI).

Main Results:

  • A structured diagnostic approach is outlined.
  • The study highlights the utility of specific MR imaging features and advanced techniques.

Conclusions:

  • Accurate diagnosis of bone marrow lesions is achievable through a systematic approach.
  • Advanced MR imaging techniques are crucial for differentiating various etiologies of bone marrow lesions.