Percutaneous coronary intervention in the elderly with ST-segment elevation myocardial infarction
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Updated: Apr 26, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
1Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.
Insights
Octogenarians with ST-segment elevation myocardial infarction (STEMI) increasingly require treatment. Percutaneous coronary intervention is preferred, but outcomes require further study to improve care for this elderly population.
Area of Science:
- Cardiology
- Geriatric Medicine
- Interventional Cardiology
Background:
- Increasing life expectancy leads to a higher proportion of octogenarians admitted for ST-segment elevation myocardial infarction (STEMI).
- Octogenarians represent a vulnerable population with higher risks of mortality and morbidity following acute cardiac events.
Purpose of the Study:
- To review the current efficacy and safety of percutaneous coronary intervention (PCI) in octogenarian patients with STEMI.
- To identify factors contributing to adverse outcomes in this demographic and explore strategies for improvement.
Main Methods:
- Literature review of recent studies on PCI for STEMI in octogenarians.
- Analysis of data regarding mortality, morbidity, and predictors of outcomes in elderly STEMI patients.
Main Results:
- Primary PCI is the recommended treatment for STEMI in octogenarians.
- Despite advances in stents and antithrombotic agents, outcomes remain controversial, with high mortality and morbidity observed in this age group.
Conclusions:
- Further research is needed to optimize PCI strategies and postoperative care for octogenarians with STEMI.
- Identifying specific predictors of mortality is crucial for tailoring interventions and improving long-term survival.
Abstract:
As a result of increased life expectancy, octogenarians constitute an increasing proportion of patients admitted to hospital for ST-segment elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention is currently the treatment of choice for octogenarians presenting with STEMI. The recent literature on this topic has yielded controversial results, even though advances in drug-eluting stents and new types of antithrombotic agents are improving the management of STEMI and postoperative care. In this paper, we review the current status of percutaneous coronary intervention in the elderly with STEMI, including the reasons for their high mortality and morbidity, predictors of mortality, and strategies to improve outcomes.
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