Design, implementation, and evaluation of a pediatric and adolescent type 2 diabetes management program at a tertiary

M Constantine Samaan1, Marlie Valencia2, Connie Cheung2

  • 1Department of Pediatrics, McMaster University, Hamilton, ON, Canada ; Division of Pediatric Endocrinology, McMaster University, Hamilton, ON, Canada ; Children's Exercise and Nutrition Center, McMaster University, Hamilton, ON, Canada.

Insights

A new multidisciplinary program improved type 2 diabetes management in youth, significantly lowering glycated hemoglobin and stabilizing BMI. This family-centered approach addresses the growing challenge of pediatric type 2 diabetes.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Public Health

Background:

  • Global incidence of type 2 diabetes in children and adolescents has risen sharply in recent decades.
  • Type 2 diabetes in pediatric populations is a relatively new phenomenon, with limited established treatment program structures.
  • Effective management strategies for pediatric type 2 diabetes comorbidities and complications are urgently needed.

Purpose of the Study:

  • To describe the design and implementation of a personalized, multidisciplinary, family-centered program for pediatric and adolescent type 2 diabetes.
  • To evaluate the program's impact on key clinical and metabolic markers in young patients.

Main Methods:

  • Implementation of a personalized, multidisciplinary, family-centered care model at a tertiary pediatric center.
  • Longitudinal assessment of patient outcomes including glycated hemoglobin, body mass index, C-peptide, and metabolic biomarkers.

Main Results:

  • Significant improvement in glycated hemoglobin levels (8% to 6.4% at 1 year, P < 0.0001).
  • Stabilization of body mass index and reduction in C-peptide levels observed.
  • No significant changes noted in fitness or metabolic biomarkers for lipid metabolism and liver function.

Conclusions:

  • A multidisciplinary, family-centered approach is effective in managing type 2 diabetes in pediatric and adolescent populations.
  • This program model shows promise in addressing the complexities of youth-onset type 2 diabetes and mitigating adverse outcomes.
  • The findings underscore the need for specialized programs to combat the increasing prevalence of type 2 diabetes in young people.

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