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Published on: June 11, 2012
Design, implementation, and evaluation of a pediatric and adolescent type 2 diabetes management program at a tertiary
M Constantine Samaan1, Marlie Valencia2, Connie Cheung2
1Department of Pediatrics, McMaster University, Hamilton, ON, Canada ; Division of Pediatric Endocrinology, McMaster University, Hamilton, ON, Canada ; Children's Exercise and Nutrition Center, McMaster University, Hamilton, ON, Canada.
Insights
A new multidisciplinary program improved type 2 diabetes management in youth, significantly lowering glycated hemoglobin and stabilizing BMI. This family-centered approach addresses the growing challenge of pediatric type 2 diabetes.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Global incidence of type 2 diabetes in children and adolescents has risen sharply in recent decades.
- Type 2 diabetes in pediatric populations is a relatively new phenomenon, with limited established treatment program structures.
- Effective management strategies for pediatric type 2 diabetes comorbidities and complications are urgently needed.
Purpose of the Study:
- To describe the design and implementation of a personalized, multidisciplinary, family-centered program for pediatric and adolescent type 2 diabetes.
- To evaluate the program's impact on key clinical and metabolic markers in young patients.
Main Methods:
- Implementation of a personalized, multidisciplinary, family-centered care model at a tertiary pediatric center.
- Longitudinal assessment of patient outcomes including glycated hemoglobin, body mass index, C-peptide, and metabolic biomarkers.
Main Results:
- Significant improvement in glycated hemoglobin levels (8% to 6.4% at 1 year, P < 0.0001).
- Stabilization of body mass index and reduction in C-peptide levels observed.
- No significant changes noted in fitness or metabolic biomarkers for lipid metabolism and liver function.
Conclusions:
- A multidisciplinary, family-centered approach is effective in managing type 2 diabetes in pediatric and adolescent populations.
- This program model shows promise in addressing the complexities of youth-onset type 2 diabetes and mitigating adverse outcomes.
- The findings underscore the need for specialized programs to combat the increasing prevalence of type 2 diabetes in young people.
Abstract:
Global rates of type 2 diabetes in children and adolescents have increased significantly over the past three decades. Type 2 diabetes is a relatively new disease in this age group, and there is a dearth of information about how to structure treatment programs to manage its comorbidities and complications. In this paper, we describe the design and implementation of a personalized multidisciplinary, family-centered, pediatric and adolescent type 2 diabetes program at a tertiary pediatric center in Hamilton, Ontario, Canada. We report the process of designing and implementing such a program, and show that this multidisciplinary program led to improvement in glycated hemoglobin (n=17, 8% at baseline versus 6.4% at 1 year, 95% confidence interval (0.1-0.28), P-value <0.0001) and stabilized body mass index, with lowered C-peptide and no change in fitness or metabolic biomarkers of lipid metabolism and liver function. As type 2 diabetes becomes more prevalent in youth, the need for programs that successfully address the complex nature of this disease is central to its management and to mitigate its long-term adverse outcomes.
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