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Chryseobacterium indologenes Septicemia in an Infant

Turkan Aydin Teke1, Fatma Nur Oz1, Ozge Metin1

  • 1Dr. Sami Ulus Maternity and Children's Research and Training Hospital, Division of Pediatric Infectious Diseases, No. 44, Altındağ, 06080 Ankara, Turkey.

Case Reports in Infectious Diseases
|August 13, 2014
PubMed

Insights

Chryseobacterium indologenes is a rare bacterial infection in children, often affecting hospitalized patients with severe conditions. Trimethoprim sulfamethoxazole effectively treated a case of nosocomial septicemia caused by this organism in an infant.

Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Antimicrobial Resistance

Background:

  • Chryseobacterium indologenes is an infrequent pathogen, primarily causing infections in immunocompromised pediatric patients.
  • Limited antimicrobial susceptibility of C. indologenes complicates treatment decisions.
  • Nosocomial infections pose a significant challenge in pediatric intensive care settings.

Purpose of the Study:

  • To report a case of Chryseobacterium indologenes septicemia in an infant with congenital heart disease.
  • To evaluate the efficacy of trimethoprim sulfamethoxazole in treating C. indologenes infections.
  • To review existing literature on pediatric C. indologenes infections.

Main Methods:

  • Case presentation of an infant with congenital heart disease and C. indologenes septicemia.
  • Retrospective review of 14 additional pediatric cases from English literature.
  • Antimicrobial susceptibility testing and treatment outcome analysis.

Main Results:

  • Successful treatment of infant septicemia with trimethoprim sulfamethoxazole.
  • C. indologenes infections are associated with significant underlying comorbidities in children.
  • Variable antimicrobial sensitivities reported across reviewed cases.

Conclusions:

  • Trimethoprim sulfamethoxazole can be an effective therapeutic option for Chryseobacterium indologenes infections in children.
  • Early diagnosis and appropriate antimicrobial selection are crucial for managing C. indologenes.
  • Further research is needed to understand the epidemiology and optimal treatment strategies for C. indologenes in pediatric populations.

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