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Blood Pressure Variability/Dipper/Non-dipper in Hypertension and Diabetes
1Department of Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.. ke112@jichi.ac.jp.
Insights
Hypertension in diabetes significantly increases complication risks. Blood pressure variability, beyond just levels, is crucial for managing diabetes-related vascular issues.
Area of Science:
- Cardiology
- Endocrinology
- Vascular Medicine
Background:
- Hypertension is a major risk factor for microvascular and macrovascular complications in diabetic patients.
- While blood pressure (BP) levels are critical, BP variability is increasingly recognized as an important factor in BP management.
Purpose of the Study:
- To review the significance of various types of blood pressure variability in patients with diabetes.
- To highlight the importance of considering BP variability alongside BP levels for comprehensive diabetes care.
Main Methods:
- Review of existing literature on blood pressure variability in diabetic populations.
- Categorization of BP variability into different timeframes: beat-to-beat, 24-hour, diurnal, day-by-day, and visit-to-visit.
Main Results:
- Blood pressure variability encompasses multiple concepts, including very short-term, short-term, diurnal, long-term, and visit-to-visit variations.
- Abnormal circadian rhythm of blood pressure is identified as a component of short-term BP variability.
- Growing body of research underscores the importance of BP variability in diabetes management.
Conclusions:
- Blood pressure variability is a critical, often overlooked, aspect of hypertension management in diabetes.
- Understanding and monitoring different types of BP variability may lead to improved prevention of vascular complications.
- Further research into the clinical implications of BP variability in diabetes is warranted.
Abstract:
It has been well recognized that hypertension in diabetes is a potent risk of micro- and macrovascular complications. BP levels are most important component of BP management. Next to BP levels, other component such as BP variability is also important. BP variability consists of several concepts [1]
1) Very Short term BP variability (beat-to-beat)
2) Short term BP variability (over the 24h)
3) Diurnal BP variation in diabetes
4) Long term BP variability (day-by-day)
5) Visit-to-Visit Variability (months ~ years)
Among these, abnormal circadian rhythm of BP belongs to short-term BP variability. There have been a number of papers about BP variability in recent years. In this chapter, the significance of BP variability in patients with diabetes will be reviewed.
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