Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

Magnetic Resonance Imaging Features in Intramedullary Tumors: A Pictorial Review.

Biomedicines·2026
Same author

Disrupted integration-segregation balance in the intact hemisphere in chronic spatial neglect.

Brain structure & function·2026
Same author

Updated French OFSEP recommendations for multiple sclerosis MRI: alignment with the 2024 McDonald criteria.

Journal of neuroradiology = Journal de neuroradiologie·2026
Same author

French NOMADMUS Cohort Overview: Landscape Evolution of AQP4+NMOSD and MOGAD From 2010 to 2024.

Neurology·2026
Same author

White matter hyperintensities in Alzheimer's disease in the era of anti-amyloid therapies.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026

Related Experiment Video

Updated: Apr 25, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

11.3K

Effector-dependent neglect and splenial disconnection: a spherical deconvolution tractography study.

Marine Lunven1, Michel Thiebaut De Schotten, Bertrand Glize

  • 1Inserm UMR_S 1028, CNRS UMR 5292, ImpAct, Centre des Neurosciences de Lyon, Université Lyon-1, 16, Avenue Lépine, 69676, Bron, France, marine.lunven@hotmail.fr.

Experimental Brain Research
|August 14, 2014
PubMed
Summary
This summary is machine-generated.

This study shows that a stroke survivor with persistent left neglect recovered when using their left hand for tasks. This suggests effector-dependent neglect may stem from damage to the corpus callosum, impacting attention networks.

More Related Videos

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.0K
DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

13.0K

Related Experiment Videos

Last Updated: Apr 25, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
13:26

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography

Published on: August 11, 2016

11.3K
Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.0K
DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions
10:05

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

13.0K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Left neglect and left homonymous hemianopia can result from right hemisphere strokes.
  • Persistent neglect, even years after stroke, poses significant challenges in rehabilitation.

Purpose of the Study:

  • To investigate effector-dependent neglect in a patient with chronic left neglect.
  • To explore the neural underpinnings of this phenomenon using advanced neuroimaging.

Main Methods:

  • Case study of a patient with right hemisphere stroke-induced left neglect.
  • Performance assessment using cancellation tasks and line bisection with both hands.
  • White matter tractography with spherical deconvolution to analyze brain connectivity.

Main Results:

  • Severe left neglect persisted on cancellation tasks with the dominant right hand 7-8 years post-stroke.
  • Normal performance on line bisection tasks regardless of hand used.
  • Cancellation task performance normalized when using the non-dominant left hand.
  • Tractography revealed damage to the splenium of the corpus callosum and preserved right fronto-parietal network.

Conclusions:

  • Splenial disconnection may cause effector-dependent neglect by disrupting interhemispheric visual information transfer to right-hemisphere attention networks.
  • Using the left hand may bypass this disconnection, engaging right-hemisphere attentional networks more directly and normalizing spatial exploration.