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Dengue encephalopathy - still an enigma?

Rupali Malik1, Arun Gogna, Jhasketan Meher

  • 1VMMC and Safdarjang Hospital, New Delhi, India. drvickyster@gmail.com.

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|August 14, 2014
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Summary

Dengue encephalopathy, a rare neurological complication of dengue fever, is increasingly reported. This case highlights unusual MRI findings in the cerebellum, brainstem, and thalami, even with normal cerebrospinal fluid.

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Dengue encephalopathy, a neurological complication of dengue infection, was historically considered rare.
  • Recent years have seen an increase in reported cases, though they remain infrequent.

Observation:

  • A confirmed case of dengue fever presented with encephalopathy.
  • Cranial magnetic resonance imaging (MRI) revealed extensive bilateral involvement of the cerebellum, brainstem, and thalami.
  • Peculiar rim enhancement was noted on MRI.

Findings:

  • The MRI findings in this dengue encephalopathy case were previously unreported.
  • Cerebrospinal fluid analysis was normal, contrasting with the extensive brain imaging abnormalities.

Implications:

  • This case expands the understanding of dengue's neurological manifestations.
  • Highlights the utility of advanced neuroimaging in diagnosing complex dengue-related neurological conditions.
  • Suggests the need for increased awareness of dengue encephalopathy in endemic regions.